Relationship between Body Mass Index, Waist-to-Hip Ratio, and Serum Lipid Concentrations and Thyroid-Stimulating Hormone in the Euthyroid Adult Population
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چکیده مقاله:
Background: The aim of this cross-sectional study was to investigate the relationship between body mass index (BMI), waist-to-hip ratio, and lipid parameters and serum thyroid-stimulating hormone (TSH) levels in healthy euthyroid individuals.Methods: This cross-sectional study was conducted between June 1st and July 20th, 2013, at Bushehr University of Medical Sciences. One hundred forty euthyroid individuals were divided into 2 groups: a high-TSH group (TSH between 2.0 and 5.5 mIU/L, n=67) and a low-TSH group (TSH between 0.3 and 2.0 mIU/L, n=73). After overnight fast, total cholesterol, triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), TSH, thyroxine (T4), and triiodothyronine (T3) were measured. Height and weight were measured with a stadiometer, and BMI was calculated as weight in kilograms divided by the square of height in meters. Waist-to-hip ratio was determined as waist circumference divided by hip circumference. The simple independent t-test and a general linear model were used for statistical analysis. All statistical analyses were done using the SPSS, version 15, statistical software package.Results: BMI and LDL-C were significantly higher in the high-TSH group than in the low-TSH group after adjustment for age, sex, calorie intake, total fat and carbohydrate intakes, and physical activity. No significant differences were found between the groups in TG, cholesterol, and HDL-C. The association between TSH levels andT4 was significant.Conclusion: Individuals with TSH levels at the upper limit of normality might be at risk of hypercholesterolemia and obesity.
منابع مشابه
relationship between body mass index, waist-to-hip ratio, and serum lipid concentrations and thyroid-stimulating hormone in the euthyroid adult population
background: the aim of this cross-sectional study was to investigate the relationship between body mass index (bmi), waist-to-hip ratio, and lipid parameters and serum thyroid-stimulating hormone (tsh) levels in healthy euthyroid individuals. methods: this cross-sectional study was conducted between june 1st and july 20th, 2013, at bushehr university of medical sciences. one hundred forty euthy...
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عنوان ژورنال
دوره 42 شماره 3
صفحات 301- 305
تاریخ انتشار 2017-01-24
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